School of Mechanical & Manufacturing Engineering
Faculty Muhammad Asghar 5

Muhammad Asghar

Professor
Summary

Dr. Muhammad Asghar is a distinguished academic and scientist currently serving as Professor, at Department of Biomedical Engineering, SMME , National University of Sciences and Technology (NUST), Islamabad, Pakistan. Dr Asghar also holds the position of Associate Professor and Ragnar Söderberg Fellow in Medicine at the Department of Biology, Lund University, Sweden and a guest researcher position at Department of Sports and Clinical Biomechanics at Southern University Denmark. Dr Asghar has completed 4 years postdoctoral training at the Department of Medicine, Karolinska Institutet, Sweden, one of the world’s premier medical research universities. Prior to his current appointment at NUST, Dr. Asghar served as Associate Professor and Group Leader at the Karolinska Institutet. Throughout his career, Dr. Asghar has built a robust profile in both scientific research and institutional development, demonstrating excellence in both domains. His research has been published in high-impact journals such as Science, Nature Medicine, Nature Communications, and Aging Cell, contributing to a cumulative impact factor exceeding 400, a reflection of the depth and influence of his scholarly work. He has also secured approximately USD 2 million in competitive research funding, a strong indicator of the trust and recognition he commands within the international scientific community. Dr Asghar pioneering contributions have earned him several prestigious international awards, including the KATMA Award (USA), TRN Award (USA).

Academic Background
PhD (Biology/Ecology) Lund University January 07, 2010 - August 15, 2013
Honours and Awards
Publications
Effects of stress on bone health in children January 07, 2026 Frontiers in Endocrinology - Volume:16, Pages:17
Infection length and host environment influence on Plasmodium falciparum dry season reservoir October 01, 2024 EMBO Molecular Medicine - Volume 16, Issue 10, Pages 2349-2375
Potential diagnostic and drug target markers in glioblastoma March 27, 2024 Scientific Reports - Vol:14, Article Number: 7292
Outlining recent updates on influenza therapeutics and vaccines: A comprehensive review March 01, 2024 Vaccine: X - Volume 17, Article Number: 100452
Football training as a non-pharmacological treatment of the global aging population—A topical review February 09, 2023 Frontiers in Aging - Volume 4, Article Number 1146058
Human influenza virus infection elicits distinct patterns of monocyte and dendritic cell mobilization in blood and the nasopharynx February 08, 2023 eLife - Volume 12, Article Number e77345
Mitochondrial biogenesis, telomere length and cellular senescence in Parkinson’s disease and Lewy body dementia October 20, 2022 Scientific Reports - Volume 12, Issue 1, Article Number 17578
Distinct kinetics of antibodies to 111 Plasmodium falciparum proteins identifies markers of recent malaria exposure January 17, 2022 Nature Communications - Volume 13, Issue 1, Article Number: 331
Comparison of low-versus high-dose steroids in the clinical outcome of hospitalized covid-19 patients December 09, 2021 Antibiotics - Volume 10, Issue 12, Article Number 1510
Beneficial effects of anticoagulants on the clinical outcomes of covid-19 patients November 13, 2021 Antibiotics - Volume 10, Issue 11, Article Number 1394
Metabolic perturbation associated with COVID-19 disease severity and SARS-CoV-2 replication November 02, 2021 Molecular and Cellular Proteomics - Volume 20, Article Number 100159
Age-related mitochondrial alterations in brain and skeletal muscle of the YAC128 model of Huntington disease October 14, 2021 npj Aging and Mechanisms of Disease - Volume 7, Issue 1, Article Number 26
Biomarkers of cellular aging during a controlled human malaria infection September 21, 2021 Scientific Reports - Volume 11, Issue 1, Article Number: 18733
Football and team handball training postpone cellular aging in women June 03, 2021 Scientific Reports - Volume 11, Issue 1, Article Number 11733
Determinants of the varied profiles of Plasmodium falciparum infections among infants living in Kintampo, Ghana May 29, 2021 Malaria Journal - Volume 20, Issue 1, Article Number 240
Hiv-exposed seronegative sex workers express low t-cell activation and an intact ectocervical tissue microenvironment March 04, 2021 Vaccines - Volume: 9, Issue:3, Page:1-19
Memory B-Cell Responses Against Merozoite Antigens After Acute Plasmodium falciparum Malaria, Assessed Over One Year Using a Novel Multiplexed FluoroSpot Assay February 12, 2021 Frontiers in Immunology - Volume 11, Article Number 619398
Increased circulation time of Plasmodium falciparum underlies persistent asymptomatic infection in the dry season December 01, 2020 Nature Medicine - Volume:26, Issue:12, Page:1929-1940
Profiles of Plasmodium falciparum infections detected by microscopy through the first year of life in Kintampo a high transmission area of Ghana October 19, 2020 Plos One - Volume 15, Issue 10, Article Number e0246773
Effectiveness of sulfadoxine–pyrimethamine for intermittent preventive treatment of malaria and adverse birth outcomes in pregnant women March 11, 2020 Pathogens - Volume:9, Issue:3, Article Number 207
A panel of recombinant proteins from human-infective Plasmodium species for serological surveillance January 17, 2020 Malaria Journal - Volume 19, Issue 1, Article Number: 31
Impact of Q-Griffithsin anti-HIV microbicide gel in non-human primates: In situ analyses of epithelial and immune cell markers in rectal mucosa December 02, 2019 Scientific Reports - Volume 9, Issue 1, Article Number: 18120
Pregnancy and CYP3A5 genotype affect day 7 plasma lumefantrine concentrations December 01, 2019 Drug Metabolism and Disposition - Volume 47, Issue 12, Pages 1415-1424
Urothelial cell senescence is not linked with telomere shortening September 01, 2019 Journal of Tissue Engineering and Regenerative Medicine - Volume:13, Issue:9, Page:1518-1527
Persistent transmission of plasmodium malariae and plasmodium ovale species in an area of declining plasmodium falciparum transmission in Eastern Tanzania May 28, 2019 PLoS Neglected Tropical Diseases - Volume:13, Issue:5, Article Number e0007414
B cell profiling in malaria reveals expansion and remodeling of CD11c+ B cell subsets May 02, 2019 JCI Insight - Volume:4, Issue:9, Article Number e126492
Antibody responses to merozoite antigens after natural Plasmodium falciparum infection: Kinetics and longevity in absence of re-exposure January 30, 2019 BMC Medicine - Volume:17, Issue:1, Article Number: 22
Liver Injury in Uncomplicated Malaria is an Overlooked Phenomenon: An Observational Study October 18, 2018 EBioMedicine - Volume 36, Pages 131-139
Cellular aging dynamics after acute malaria infection: A 12-month longitudinal study February 01, 2018 Aging Cell - Volume 17, Issue 1, Article Number e12702
Detection of Malaria Parasites After Treatment in Travelers: A 12-months Longitudinal Study and Statistical Modelling Analysis November 15, 2017 EBioMedicine - Volume 25, Pages 66-72
Pale and dark morphs of tawny owls show different patterns of telomere dynamics in relation to disease status July 26, 2017 Proceedings of the Royal Society B: Biological Sciences - Volume 284, Issue 1859, Pages 1-8
Effect of pharmacogenetics on plasma lumefantrine pharmacokinetics and malaria treatment outcome in pregnant women July 03, 2017 Malaria Journal - Volume 16, Issue 1, Article Number: 267
High Rate of Treatment Failures in Nonimmune Travelers Treated With Artemether-Lumefantrine for Uncomplicated Plasmodium falciparum Malaria in Sweden: Retrospective Comparative Analysis of Effectiveness and Case Series January 15, 2017 Clinical Infectious Diseases - Volume 64, Issue 2, Pages 199-206
Parallel telomere shortening in multiple body tissues owing to malaria infection August 17, 2016 Proceedings of the Royal Society B: Biological Sciences - Volume 283, Issue 1836, Pages 1-7
A rare study from the wintering grounds provides insight into the costs of malaria infection for migratory birds July 01, 2016 Journal of Avian Biology - Volume 47, Issue4, Pages 575-582
Skin pentosidine and telomere length do not covary with age in a long-lived seabird August 01, 2015 Biogerontology - Volume 16, Issue 4, Pages 435-441
Hidden costs of infection: Chronic malaria accelerates telomere degradation and senescence in wild birds January 23, 2015 Science - Volume 347, Issue 6220, Pages 436-438
Maternal and genetic factors determine early life telomere length January 22, 2015 Proceedings of the Royal Society B: Biological Sciences - Volume 282, Issue 1799, Pages 1-9
Co-infections by malaria parasites decrease feather growth but not feather quality in house martin September 01, 2013 Journal of Avian Biology - Volume 44, Issue 5, Pages 437-444
Primary peak and chronic malaria infection levels are correlated in experimentally infected great reed warblers September 01, 2012 Parasitology - Volume 139, Issue 10, Pages 1246-1252
A new morphologically distinct avian malaria parasite that fails detection by established polymerase chain reactionbased protocols for amplification of the cytochrome B gene June 01, 2012 Journal of Parasitology - Volume 98, Issue 3, Pages 657-665
Quantitative disease resistance: To better understand parasite-mediated selection on major histocompatibility complex February 01, 2012 Proceedings of the Royal Society B: Biological Sciences - Volume 279, Issue 1728, Pages 577-584
Are chronic avian haemosporidian infections costly in wild birds? November 01, 2011 Journal of Avian Biology - Volume 42, Issue 6, Pages 530-537
Conferences
Senior Researcher/Docent Lund University April 11, 2022 - February 20, 2023
Docent/Associate Professor Karoliska Institutet, Sweden August 25, 2021 - April 10, 2022
Senior Researcher Karoliska Institutet, Sweden April 01, 2019 - April 09, 2022
Assistant Professor Karoliska Institutet, Sweden December 01, 2017 - November 30, 2019
Postdoctoral Fellow Karoliska Institutet, Sweden September 01, 2013 - November 30, 2017
Postdoctoral Fellow Lund University October 02, 2012 - August 31, 2013