Faculty Saima Zafar

Saima Zafar

Professor
  • School of Mechanical & Manufacturing Engineering
  • 0519086057
Summary

Academic Background
PhD (Neuroscinces) Georg-August Universität Göttingen June 01, 2007 - January 17, 2011
Honours and Awards
HAI-IDR Research grant- Helmholtz-Alberta Initiative-Infectious Diseases Research (HAI-IDR) November 06, 2013
University of the Punjab Gold Medal, Role of Honor, B.Sc (Hons.) Department of Zoology, University of the Punjab, Lahore, Pakistan July 22, 2003
University of the Punjab Gold Medal, Role of Honor, M.Sc. Department of Zoology, University of the Punjab, Lahore, Pakistan November 27, 2004
European Union (EU) Ph.D. fellowship, 6th framework European Union (EU)- funded project, “Identification of potential biomarkers of CJD using STrEPTM technology and proteomics”. March 14, 2007
UMG germany Post-Doctoral fellowship, DGKL-funding, “Kidney fibrosis and Mycophenolic acid” January 03, 2011
European Union Post-Doctoral fellowship, Protecting the food chain from prions (Priority) European Union (EU) funded projects to evaluate the epidemiology and surveillance of CJD subtypes May 01, 2011
University of the Punjab Merit Scholarship, University of the Punjab, Lahore, Pakistan January 01, 2020
Human prions Research grant- Human prions – distinguishing sporadic from familial forms via structure and function – 201300024 February 06, 2013
Publications
Genome wide association study of clinical duration and age at onset of sporadic CJD July 26, 2024 Holger Hummerich, Helen Speedy, Tracy Campbell, Lee Darwent, Elizabeth Hill, Steven Collins, Christiane Stehmann, Gabor G Kovacs, Michael D Geschwind , Karl Frontzek, Herbert Budka, Ellen Gelpi, Adriano Aguzzi, Sven J van der Lee, Cornelia M. van Duijn, Pawel P. Liberski, Miguel Calero, Pascual Sanchez-Juan, Elodie Bouaziz-Amar, Jean-Louis Laplanche, Ste´phane Haïk, Jean-Phillipe Brandel, Angela Mammana, Sabina Capellari, Anna Poleggi, Anna Ladogana, Maurizio Pocchiari, Saima Zafar, Stephanie Booth, Gerard H. Jansen, Aušrinė Areškevičiūtė, Eva Løbner Lund, Katie Glisic, Piero Parchi, Peter Hermann, Inga Zerr , Brian S. Appleby, Jiri Safar, Pierluigi Gambetti, John Collinge, Simon Mead, Plos One - Volume 19(7), Article Number e0304528
Prevention of Chronic Diabetic Neuropathy and Diabetes-Associated Cognitive Impairment Using Medicinal Herbs (Cassia Angustifolia and Nigella Sativa) June 28, 2024 Mahum Khan, Hibba Riaz, Faria Hasan Jatala, Aneeqa Noor, Sara Mumtaz, Saima Zafar, The Yale Journal of Biology and Medicine - Volume 97(2), Pages 141-152
Therapeutic Potential of Nitrogen-Doped Rutin-Bound Glucose Carbon Dots for Alzheimer’s Disease June 28, 2024 Sana Khan, Faria Hasan Jatala, Alveena Muti, Noor Afza, Aneeqa Noor, Sara Mumtaz, Saima Zafar, The Yale Journal of Biology and Medicine - Volume 97(2), Pages 153-164
A systemic analysis of Creutzfeldt Jakob disease cases in Asia February 07, 2024 Urwah Rasheed, Sana Khan, Minahil Khalid, Aneeqa Noor, Saima Zafar, Prion - Volume 18, Issue 1, Pages: 11-27
Current Technologies Unraveling the Significance of Post-Translational Modifications (PTMs) as Crucial Players in Neurodegeneration January 16, 2024 Saima Zafar, Shehzadi Irum Fatima, Matthias Schmitz, Inga Zerr, Biomolecules - Volume 14(1), Article Number 118
Differential interactome mapping of aggregation prone/prion-like proteins under stress: novel links to stress granule biology December 01, 2023 Neelam Younas, Saima Zafar, Tayyaba Saleem, Leticia Camila Fernandez Flores, Abrar Younas, Matthias Schmitz, Inga Zerr, Cell and Bioscience - Volume 13, Issue 1, Article Number 221
Genetic Variants Associated with the Age of Onset Identified by Whole-Exome Sequencing in Fatal Familial Insomnia August 12, 2023 Katrin Thüne, Matthias Schmitz, John Wiedenhöft, Orr Shomroni, Stefan Göbe, Timothy Bunck, Neelam Younas, Saima Zafar, Peter Hermann, Inga Zerr, Cells - Volume 12, Issue 16, Article Number 2053
The Role of Tau Proteoforms in Health and Disease June 02, 2023 Zuha Waheed, Jawaria Choudhary, Faria Hasan Jatala, Fatimah, Aneeqa Noor, Inga Zerr, Saima Zafar, Molecular Neurobiology - Pages 1-12
α-Synuclein conformers reveal link to clinical heterogeneity of α-synucleinopathies March 14, 2023 Matthias Schmitz, Niccolò Candelise, Sezgi Canaslan, Hermann C. Altmeppen, Jakob Matschke, Markus Glatzel, Neelam Younas, Saima Zafar, Peter Hermann, Inga Zerr, Translational Neurodegeneration - Volume:12, Issue:1, Article Number: 12
SWATH Mass Spectrometry-Based CSF Proteome Profile of GBA-Linked Parkinson’s Disease Patients November 16, 2022 Saima Zafar, Aneeqa Noor, Neelam Younas, Mohsin Shafiq, Matthias Schmitz, Isabel Wurster, Kathrin Brockmann, Thomas Gasser, Inga Zerr, International Journal of Molecular Sciences - Volume 23(22), Article Number 14166
Clinical Proteomics: Diagnostics and Prognostic Markers of Cancer June 28, 2022 Saima Zafar, Aniqa Saeed, Saadia Zahid, Book on Cancer Biomarkers in Diagnosis and Therapeutics - 1st Edition, Chapter 4, Pages 83-99
Molecular Profiles of Amyloid-β Proteoforms in Typical and Rapidly Progressive Alzheimer's Disease January 01, 2022 Aneeqa Noor, Saima Zafar, Mohsin Shafiq, Neelam Younas, Anna Siegert, Florian A Mann, Sebastian Kruss, Mathias Schmitz , Hassan Dihazi, Isidre Ferrer, Inga Zerr, Molecular Neurobiology - Volume 59, Pages 17-34
Molecular Profles of Amyloid‑β Proteoforms in Typical and Rapidly Progressive Alzheimer’s Disease October 07, 2021 Aneeqa Noor , Saima Zafar, Mohsin Shafiq , Neelam Younas , Anna Siegert , Florian A. Mann , Sebastian Kruss , Matthias Schmitz , Hassan Dihazi , Isidre Ferrer , Inga Zerr, Molecular Neurobiology - Pages 1-18
Cellular Prion Protein Mediates α‐Synuclein Uptake, Localization, and Toxicity In Vitro and In Vivo August 27, 2021 Tobias Thom, Matthias Schmitz, Anna-Lisa Fischer, Angela Correia, Susana Correia, Franc Llorens, Anna-Villar Pique, Wiebke Möbius, Renato Domingues, Saima Zafar, Erik Stoops, Christopher J. Silva, Andre Fischer, Tiago F. Outeiro, Inga Zerr, Movement Disorders - Pages 1-14
Distribution of microRNA profiles in pre-clinical and clinical forms of murine and human prion disease March 25, 2021 Lesley Cheng, Camelia Quek, Xia Li, Shayne A. Bellingham, Laura J. Ellett, Mitch Shambrook, Saima Zafar, Inga Zerr, Victoria A. Lawson, Andrew F. Hill, Communications Biology - Volume 4(1), Article Number 411
Prion protein oligomers cause neuronal cytoskeletal damage in rapidly progressive Alzheimer’s disease February 22, 2021 Mohsin Shafiq, Saima Zafar, Neelam Younas, Aneeqa Noor, Berta Puig, Hermann Clemens Altmeppen, Matthias Schmitz, Jakob Matschke, Isidre Ferrer, Markus Glatzel, Inga Zerr, Molecular Neurodegeneration - Volume 16, Issue 1, Article Number: 11
Neurodegenerative Proteinopathies in the Proteoform Spectrum -Tools and Challenges January 22, 2021 Aneeqa Noor, Saima Zafar, Inga Zerr, International Journal of Molecular Sciences - Volume 22(3), Article Number 1085
Optimization of the Real-Time Quaking-Induced Conversion Assay for Prion Disease Diagnosis November 19, 2020 Inga Zerr, Maria Cramm, Susana Margarida da Silva Correia, Saima Zafar, Anna Villar-Piqué, Franc Llorens, Matthias Schmitz, Frontiers in Bioengineering and Biotechnology - Volume 8, Article Number 586890
Identification of novel risk loci and causal insights for sporadic Creutzfeldt-Jakob disease: a genome-wide association study October 01, 2020 Emma Jones, Holger Hummerich, Emmanuelle Viré, James Uphill , Athanasios Dimitriadis, Helen Speedy, Tracy Campbell, Penny Norsworthy, Liam Quinn, Jerome Whitfield, Jacqueline Linehan, Zane Jaunmuktane, Sebastian Brandner, Parmjit Jat, Akin Nihat, Tze How Mok, Parvin Ahmed , Steven Collins , Christiane Stehmann, Shannon Sarros, Gabor G Kovacs, Michael D Geschwind, Aili Golubjatniko, Karl Frontzek, Herbert Budka, Adriano Aguzzi, Hata Karamuji?-?omi?, Sven J van der Lee, Carla A Ibrahim-Verbaas, Cornelia M van Duijn , Beata Sikorska, Ewa Golanska, Pawel P Liberski, Miguel Calero, Olga Calero, Pascual Sanchez-Juan, Pascual Sanchez-Juan, Antonio Salas, Federico Martinón-Torres, Elodie Bouaziz-Amar, Stéphane Haïk, Jean-Louis Laplanche , Jean-Phillipe Brandel, Phillipe Amouyel, Jean-Charles Lambert, Piero Parchi, Anna Bartoletti-Stella, Sabina Capellari, Anna Poleggi, Maurizio Pocchiari, Saima Zafar, Prof Simon Mead , Serena Aneli , Giuseppe Matullo, Katie Glisic, Inga Zerr, Brian Appleby, Pierluigi Gambetti, Gerard H Jansen, Jiri Safar, John Collinge, Lancet Neurology - Volume 19, Issue 10, Pages 840-848
Unveiling the Physical and Functional Niches of FAM26F by Analyzing Its Subcellular Localization and Novel Interacting Partners August 25, 2020 Uzma Malik, Saima Zafar, Neelam Younas, Inga Zerr, Aneela Javed, ACS Omega - Volume 5(35), Pages 22008-22020
SFPQ and Tau: critical factors contributing to rapid progression of Alzheimer’s disease June 23, 2020 Neelam Younas, Saima Zafar, Mohsin Shafq, Aneeqa Noor, Anna Siegert, Amandeep Singh Arora, Alexey Galkin, Ayesha Zafar, Mathias Schmitz, Christine Stadelmann-Nessler, Olivier Andréoletti, Isidre Ferrer, Inga Zerr, Acta Neuropathologica - Pages 1-23
Genome-wide association study identifies risk variants for sporadic Creutzfeldt-Jakob disease in STX6 and GAL3ST1 April 11, 2020 Emma Jones, Holger Hummerich, Emmanuelle Viré, James Uphill, Saima Zafar, medRxiv - CC-BY-NC 4.0 International license - Cold Spring Harbor Laboratory - Pages 1-32
The role of cellular prion protein in lipid metabolism in the liver March 05, 2020 Amandeep Singh Arora, Saima Zafar, Umair Latif, Franc Llorens, Sabine Mihm, Prateek Kumar, Waqas Tahir, Katrin Thüne, Mohsin Shafiq, Matthias Schmitz, Inga Zerr, Prion - Volume 14, No. 1, Pages 95-108
Chromogranin A Analysis in the Differential Diagnosis Across Lewy Body Disorders. February 18, 2020 Karin Gmitterova, Daniela Varges, Matthias Schmitz, Saima Zafar, Fabian Maass, Paul Lingor, Inga Zerr, Journal of Alzheimer's Disease - Volume 73, No. 4, Pages 1355-1361
Effect of the micro-environment on α-synuclein conversion and implication in seeded conversion assays January 17, 2020 Niccolo Candelise, Matthias Schmitz, Katrin Thüne, Maria Cramm, Alberto Rabano, Saima Zafar, Erik Stoops, Hugo Vanderstichele, Anna Villar-Pique, Franc Llorens, Inga Zerr, Translational Neurodegeneration - Vol. 9, Article Number 5, Pages 1-16
Therapies for Prion Diseases November 11, 2019 Saima Zafar, Aneeqa Noor, INGA ZERR, Handbook of Clinical Neurology - Chapter 4, Volume 165, Pages 47-58
The cellular prion protein and its derived fragments in human prion diseases and their role as potential biomarkers September 26, 2019 Katrin Thüne, Matthias Schmitz, Anna Villar-Piqué, Altmeppen HC, Schlomm M, Saima Zafar, Glatzel M, Llorens F, Zerr I, Expert Review of Molecular Diagnostics - 1-12
Increased expression of heme-binding protein 1 1 early in Alzheimer's 2 disease is linked to neurotoxicity August 27, 2019 Oleksandr Yagensky, Mahdokht Kohansal-Nodehi, Saravanan Gunaseelan, Tamara Rabe, Saima Zafar, Inga Zerr, Wolfgang Härtig, Henning Urlaub, John JE Chua, eLife - Volume 8, No e47498
Cadmium induces GAPDH- and- MDH mediated delayed cell aging and dysfunction in Candida tropicalis 3Aer. August 01, 2019 Zaman Khan, Muhammad Atif Nisar , Saima Zafar, Saima Zafar, Inga Zerr , Abdul Rehman, Environmental Monitoring and Assessment - Volume 191, Issue 8, Article Number 490
Cerebrospinal fluid total and phosphorylated α-synuclein in patients with Creutzfeldt–Jakob disease and synucleinopathy May 01, 2019 Matthias Schmitz, Anna Villar-Piqué, Franc Llorens, Karin Gmitterová,, Peter Hermann, Daniela Varges, Saima Zafar, Paul Lingor, Hugo Vanderstichele, Leentje Demeyer, Erik Stoops, John Q Trojanowski, Virginia M-Y Lee, Inga Zerr, Molecular Neurobiology - Volume 56, Pages 3476-3483
Seeding variability of different alpha synuclein strains in synucleinopathies. May 01, 2019 Niccolò Candelise, Matthias Schmitz, Franc Llorens, Anna Villar-Piqué, Maria Cramm, Tobias Thom, Susana Margarida da Silva Correia, José Eriton Gomes da Cunha, Wiebke Möbius, Tiago F. Outeiro, Valentina González Alvarez, Martina Banchelli , Cristiano D’Andrea , Marella de Angelis, Saima Zafar, Alberto Rabano, Paolo Matteini , Inga Zerr , Annals of Neurology - Volume 85, Issue 5, Pages 691-703
Prion Protein Strain Diversity and Disease Pathology November 05, 2018 Saima Zafar, Neelam Younas, Mohsin Shafiq, Inga Zerr, Book on Prions - Some Physiological and Pathophysiological Aspects - Chapter 4, Pages 1-16
Cytoskeleton-Associated Risk Modifiers Involved in Early and Rapid Progression of Sporadic Creutzfeldt-Jakob Disease May 01, 2018 Saima Zafar, Neelam Younas, Nadeem Sheikh, Waqas Tahir, Mohsin Shafiq, Matthias Schmitz, Isidre Ferre, Olivier Andréoletti , Inga zerr, Molecular Neurobiology - Volume 55, Pages 4009–4029
Validation of α-synuclein as a CSF biomarker for sporadic Creutzfeldt-Jakob disease March 01, 2018 Franc Llorens, Niels Kruse, André Karch, Matthias Schmitz, Saima Zafar, Nadine Gotzmann, Ting Sun, Silja Köchy, Tobias Knipper, Maria Cramm, Ewa Golansk, Beata Sikorska, Pawel P. Liberski, Raquel Sánchez-Valle, Andre Fischer, Brit Mollenhauer, Inga Zerr, Molecular Neurobiology - Volume 55, Pages 2249–2257
Animal TSEs and public health: What remains of past lessons? February 08, 2018 Saima Zafar, Mohsin Shafiq, Olivier Andreoletti, Inga zerr, PLoS Pathogens - Volume 14(2), Article Number e1006759
Regional and subtype-dependent miRNA signatures in sporadic Creutzfeldt-Jakob disease are accompanied by alterations in miRNA silencing machinery and biogenesis January 22, 2018 Franc Llorens , Katrin Thüne, Eulàlia Martí, Dimitra Dafou, Ana Vivancos, Daniela D?az-Lucena, Orr Shomroni, Saima Zafar, Matthias Schmitz, Uwe Michel, Natalia Ferna´ndez-Borges, Olivier Andre´oletti, Jose Antonio del R?o, Juana D?ez, Andre Fischer, Stefan Bonn, Theodoros Sklaviadis, Juan Maria Torres, Isidre Ferrer, Inga Zerr, PLoS Pathogens - Volume 14(1), Article Number e1006802
Cerebrospinal fluid in Creutzfeldt-Jakob disease January 01, 2018 Inga Zerr, Saima Zafar, Matthias Schmitz, Franc Llorens, Handbook of Clinical Neurology (3rd series) Cerebrospinal Fluid in Neurologic Disorders - Chapter 8, Volume 146, Pages 115-124
Molecular Alterations in the Cerebellum of Sporadic Creutzfeldt–Jakob Disease Subtypes with DJ-1 as a Key Regulator of Oxidative Stress January 01, 2018 Waqas Tahir, Saima Zafar, Franc Llorens, Amandeep Singh Arora, Katrin Thüne, Matthias Schmitz, Nadine Gotzmann, Niels Kruse, Brit Mollenhauer, Juan Maria Torres, Olivier Andréoletti , Isidre Ferrer, Inga Zerr , Molecular Neurobiology - Volume 55, Pages 517–537
Cellular prion protein mediates early apoptotic proteome alternation and phospho-modification in human neuroblastoma cells January 01, 2018 Saima Zafar, Christina Behrens, Hassan Dihazi, Matthias Schmitz, Inga Zerr, Walter J Schulz-Schaeffer, Sanja Ramljak, Abdul R Asif, Cell Death & Disease - Volume 8, Article Number 2557
Molecular basis of Cd+ 2 stress response in Candida tropicalis October 01, 2017 Zaman Khan, Muhammad Atif Nisar, Saima Zafar, Syed Zajif Hussain, Inga Zerr, Irshad Hussain, Muhammad Waseem, Muhammad Arif, Applied Microbiology and Biotechnology - Volume 101, Pages 7715–7728
Applications of the real-time quaking-induced conversion assay in diagnosis, prion strain-typing, drug pre-screening and other amyloidopathies August 14, 2017 Niccolò Candelise, Matthias Schmitz, Susana Margarida Da Silva Correia,, Amandeep Singh Arora, Anna Villar-Pique, Saima Zafar, Franc Llorens, Maria Cramm, Inga Zerr, Expert Review of Molecular Diagnostics - Volume 17, Issue 10, Pages 897-904
Prion Protein Interactome: Identifying Novel Targets in Slowly and Rapidly Progressive Forms of Alzheimer’s Disease July 03, 2017 Saima Zafar, Mohsin Shafiq, Neelam Younas, Matthias Schmitz, Isidre Ferrer, Inga Zerr, Journal of Alzheimer's Disease - Volume 59, No. 1, Pages 265-275
Subtype Specific CSF Biomarkers in Sporadic Creutzfeldt-Jakob Disease June 07, 2017 Saima Zafar, Neelam Younas, Inga Zerr, Journal of Alzheimer’s Disease & Parkinsonism - Volume 7, Issue 3, Article Number 1000332
Evaluation of α-synuclein as a novel cerebrospinal fluid biomarker in different forms of prion diseases June 01, 2017 Franc Llorens, Niels Kruse, Matthias Schmitz, Nadine Gotzmann, Ewa Golanska, Katrin Thüne, Orgeta Zejneli, Eirini Kanata, Tobias Knipper, Maria Cramm, Peter Lange, Saima Zafar, Beata Sikorska, Pawel P Liberski, Eva Mitrova, Daniela Varges, Christian Schmidt, Theodoros Sklaviadis, Brit Mollenhauer, Inga Zerr, Alzheimer's and Dementia - Volume 13, Issue 6, Pages 710-719
Effect of Metformin on Adult Hippocampal Neurogenesis: Comparison with Donepezil and Links to Cognition May 01, 2017 Sara Ahmed, Zahra Mahmood, Aneela Javed, Shoaib Naiyer Hashmi, Inga Zerr, Saima Zafar, Saadia Zahid, Journal of Molecular Neuroscience - Volume 62, Issue 1, Pages 88-98
Biosorption behavior and proteomic analysis of Escherichia coli P4 under cadmium stress May 01, 2017 Zaman Khan, Abdul Rehman, Muhammad Atif Nisar, Saima Zafar, Inga Zerr, Chemosphere - Volume 174, Pages 136-147
Altered Ca2+ homeostasis induces Calpain-Cathepsin axis activation in sporadic Creutzfeldt-Jakob disease April 27, 2017 Franc Llorens, Katrin Thüne, Beata Sikorska, Matthias Schmitz, Waqas Tahir, Natalia Fernández-Borges, Maria Cramm, Nadine Gotzmann, Margarita Carmona, Nathalie Streichenberger, Uwe Michel, Saima Zafar, Anna-Lena Schuetz, Ashish Rajput, Olivier Andréoletti, Stefan Bonn, Andre Fischer, Pawel P Liberski, Juan Maria Torres, Isidre Ferrer , Inga Zerr, Acta Neuropathologica Communications - Volume 5(1), Article Number 35
Dementia with Lewy bodies: molecular pathology in the frontal cortex in typical and rapidly progressive forms March 13, 2017 Paula Garcia-Esparcia, Irene Lopez-Gonzalez, Oriol Grau-Rivera, María Francisca García-Garrido, Anusha Konetti, Franc Llorens, Saima Zafar, Margarita Carmona, José Antonio del Rio, Inga Zerr, Ellen Gelpi, Isidro Ferrer, Frontiers in Neurology - Volume 8, Article Number 89
Strain-specific altered regulatory response of Rab7a and Tau in Creutzfeldt-Jakob disease and Alzheimer’s disease January 01, 2017 Saima Zafar, Neelam Younas, Susana Correia, Mohsin Shafiq, Waqas Tahir, Matthias Schmitz, Isidre Ferrer, Olivier Andréoletti, Inga Zerr, Molecular Neurobiology - Volume 54, Pages 697-709
Regulation of human cerebrospinal fluid malate dehydrogenase 1 in sporadic Creutzfeldt-Jakob disease patients November 14, 2016 Matthias Schmitz, Franc Llorens, Alexander Pracht, Tobias Thom, Ângela Correia, Saima Zafar, Isidre Ferrer, Inga Zerr, Aging - Volume 8(11), Pages 2927–2935
Stratification by genetic and demographic characteristics improves diagnostic accuracy of cerebrospinal fluid biomarkers in rapidly progressive dementia October 18, 2016 André Karch, Franc Llorens, Matthias Schmitz, Amandeep Singh Arora, Saima Zafar, Peter Lange, Christian Schmidt, Inga Zerr, Journal of Alzheimer's Disease - Volume 54(4), Pages 1385-1393
The real-time quaking-induced conversion assay for detection of human prion disease and study of other protein misfolding diseases October 13, 2016 Matthias Schmitz, Maria Cramm, Franc Llorens, Dominik Müller-Cramm, Steven Collins, Ryuichiro Atarashi, Katsuya Satoh, Christina D Orrù, Bradley R Groveman, Saima Zafar, Walter J Schulz-Schaeffer, Byron Caughey, Inga Zerr, Nature Protocols - Volume 11(11), Pages 2233–2242
Application of an in vitro-amplification assay as a novel pre-screening test for compounds inhibiting the aggregation of prion protein scrapie July 07, 2016 Matthias Schmitz, Maria Cramm, Franc Llorens, Niccolò Candelise, Dominik Müller-Cramm, Daniela Varges, Walter J. Schulz-Schaeffe, Saima Zafar, Inga Zerr, Scientific Reports - Volume 6, Article Number 28711
Application of capillary immunoelectrophoresis revealed an ageand gender-dependent regulated expression of PrPC in liver December 01, 2015 Amandeep Singh Arora, Saima Zafar, Otto Kollmar , Franc Llorens , Waqas Tahir, Sven Vanselow, Prateek Kumar, Mary Jo Schmerr, Matthias Schmitz, Inga Zerr, Electrophoresis - Volume 36, Issue 24, Pages 3026-3033
Novel Biomarkers and the Diagnosis of Prion Diseases November 26, 2015 Saima Zafar, Neelam Younas, Inga Zer, Journal of Molecular Biomarkers & Diagnosis - Volume 8, Pages 1-4
Quantification of CSF biomarkers using an electrochemiluminescence-based detection system in the differential diagnosis of AD and sCJD October 01, 2015 Franc Llorens, Niels Kruse, Matthias Schmitz, Mohsin Shafiq, Jose Eriton Gomes da Cunha, Nadine Gotzman, Saima Zafar, Katrin Thune, Joao Ricardo Mendes de Oliveira, Brit Mollenhauer, Inga zerr, Journal of Neurology - Volume 262, Pages 2305-2311
Cytokine profiles and the role of cellular prion protein in patients with vascular dementia and vascular encephalopathy September 01, 2015 Matthias Schmitz, Peter Hermann, Pantelis Oikonomou , Katharina Stoeck, Elisabeth Ebert, Tatjana Poliakova, Christian Schmidt, , Franc Llorens , Saima Zafar, Inga zerr, Neurobiology of Aging - Volume 36, Issue 9, Pages 2597-2606
Cellular prion protein directly interacts with and enhances lactate dehydrogenase expression under hypoxic conditions September 01, 2015 Sanja Ramljak, Matthias Schmitz, Saima Zafar, Arne Wrede, Sara Schenkel, Abdul R Asif, Julie Carimalo, Thorsten R Doeppner, Walter J Schulz-Schaeffer, Jens Weise, Inga zerr, Experimental Neurology - Volume 271, Pages 155-167
Subtype and regional regulation of prion biomarkers in sporadic Creutzfeldt–Jakob disease August 01, 2015 Franc Llorens, Saima Zafar, Belén Ansoleaga, Mohsin Shafiq, Rosi Blanco, Marga Carmona, Oriol Grau-Rivera, Carlos Nos, Ellen Gelpí, José Antonio Del Río, Inga Zerr, Isidre Ferrer, Neuropathology and Applied Neurobiolog - Volume 41, Issue 5, Pages 631-645
Cerebrospinal fluid tau levels are a marker for molecular subtype in sporadic Creutzfeldt-Jakob disease May 01, 2015 Andre Karch, Peter Hermann, Claudia Ponto, Matthias Schmitz , Amandeep Arora, Saima Zafar, Franc Llorens , Annika Muller-Heine, Inga Zerr, Neurobiology of Aging - Volume 36, Issue 5, Pages 1964-1968
Characteristic CSF prion seeding efficiency in humans with prion diseases February 01, 2015 Maria Cramm, Matthias Schmitz, André Karch , Saima Zafar , Daniela Varges, Eva Mitrova , Bjoern Schroeder, Alex Raeber, Franziska Kuhn, Inga Zerr, Molecular Neurobiology - Volume 51, Issue 1, Pages 396-405
Subtype and regional-specific neuroinflammation in sporadic Creutzfeldt–Jakob disease August 04, 2014 Franc Llorens, Irene López-González, Katrin Thüne, Margarita Carmona, Saima Zafar, Olivier Andréoletti, Inga Zerr, Isidre Ferrer, Frontiers in Aging Neuroscience - Volume 6, Article Number 198
Anchorless 23–230 PrP C Interactomics for Elucidation of PrP C Protective Role June 01, 2014 Saima Zafar, Abdul R Asif, Sanja Ramljak, Waqas Tahir, Matthias Schmitz, Inga Zerr, Molecular Neurobiology - Volume 49, Issue 3, Pages 1385-1399
Association of prion protein genotype and scrapie prion protein type with cellular prion protein charge isoform profiles in cerebrospinal fluid of humans with sporadic or familial prion diseases May 01, 2014 Matthias Schmitz, Katharina Lüllmann, Saima Zafar, Elisabeth Ebert, Marie Wohlhage, Panteleimon Oikonomou, Markus Schlomm, Eva Mitrova, Michael Beekes, Inga Zerr, Neurobiology of Aging - Volume 35, Issue 5, Pages 1177-1188
Subtype and regional regulation of prion biomarkers in sporadic Creutzfeldt-Jakob disease April 01, 2014 Franc Llorens, Saima Zafar, Belén Ansoleaga, Mohsin Shafiq, Rosi Blanco, Marga Carmona, Ellen Gelpí, José Antonio del Río, Inga Zerr, Isidre Ferrer, Prion - Volume 8, Page121-121
Detection of infectivity in blood of persons with variant and sporadic Creutzfeldt-Jakob disease January 01, 2014 Jean Yves Douet , Saima Zafar, Armand Perret-Liaudet, Caroline Lacroux, Séverine Lugan, Naima Aron, Herve Cassard, Claudia Ponto, Fabien Corbière, Juan Maria Torres, Inga Zerr , Olivier Andreoletti, Emerging Infectious Diseases - Volume 20, Issue 1, Pages 114-117
Impact of the Cellular Prion Protein on Amyloid-β and 3PO-Tau Processing January 01, 2014 Matthias Schmitz, Katharina Wulf, Sandra C Signore, Walter J Schulz-Schaeffer, Pawel Kermer, Mathias Bähr, Fred S Wouters, Saima Zafar, Inga Zerr, Journal of Alzheimer's Disease - Volume 38, Issue 3, Pages 551-565
Kinases (Protein Kinases) May 01, 2013 Saima Zafar, Inga Zerr, Book on Brenner's Encyclopedia of Genetics (2nd Edition) - Pages 166-167
Proteomics approach to identify the interacting partners of cellular prion protein and characterization of Rab7a interaction in neuronal cells May 23, 2011 Saima Zafar, Nicolas von Ahsen, Michael Oellerich, Inga Zerr, Walter J Schulz-Schaeffer, Victor W Armstrong, Abdul R Asif, Journal of Proteome Research - Volume 10, Issue 7, Pages 3123-3135
Conferences
principle investigator Neurology, Universitätsmedizin Göttingen (UMG), January 01, 2011 - December 31, 2018
research scientist Department of Clinical Chemistry, Universitätsmedizin Göttingen (UMG), June 01, 2007 - April 30, 2011